Utilization of Nanomaterials in Target Oriented Drug Delivery Vehicles

Carbon Nanomaterials for Drug Delivery

Carbon nanomaterials with unique nanostructure (CMNS) are the most studied materials in nanotechnology, despite some conflicting results about their safety profiles [1, 2]. Although their structures are simple, carbon nanomaterials provide exceptional physical and chemical properties including high electrical and thermal conductivities, unique optical properties, and extreme chemical stability....

Biomedical Approach of Nanomaterials for Drug Delivery

The objective of this paper is to highlight the diversity of nanomaterials, their advance applications and current demand for technology. Nanomaterials manifest extremely fascinating and useful properties which can be exploited for a variety of structural and nonstructural applications. Since some techniques have disadvantages such as low bio-availability, rapid clearance, and less efficiency. ...

Poloxamine-based nanomaterials for drug delivery.

Poloxamines (Tetronic) are X-shaped amphiphilic block copolymers formed by four arms of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) blocks bonded to a central ethylenediamine moiety. Such a structure confers multi-responsive behaviour, namely temperature and pH-sensitiveness. At relatively low concentrations but above the critical micellar concentration (CMC), poloxamines generate poly...

Design and evaluation of drug delivery vehicles

A crucial aspect of drug delivery is efficient transport to the site of action. Thus, there is a need to design and evaluate new delivery vehicles. In this thesis two delivery vehicles, cell-penetrating peptides and bacterial ghosts, were evaluated. The understanding of the internalization and degradation kinetics of cell-penetrating peptides is important for the practical aspects of cargo deli...

Polymeric micelles as drug delivery vehicles